jo300225z_si_001.pdf (1.93 MB)
Biomimetic Total Synthesis of Cruentaren A via Aromatization of Diketodioxinones
journal contribution
posted on 2012-04-06, 00:00 authored by Marianne Fouché, Lisa Rooney, Anthony G. M. BarrettThe total synthesis of cruentaren A, a biologically active
resorcylate natural product, is reported. The aromatic unit was constructed
via late-stage cyclization and aromatization from a diketodioxinone
intermediate and macrocyclization using Fürstner ring-closing
alkyne metathesis.