Asymmetric Hydrogenation
of Thiophenes and Benzothiophenes

Urban, Slawomir; Beiring, Bernhard; Ortega, Nuria; Paul, Daniel; Glorius, Frank

doi:10.1021/ja306622y.s001

ja306622y_si_001.pdf (4.33 MB)

Asymmetric Hydrogenation of Thiophenes and Benzothiophenes

journal contribution

posted on 2012-09-19, 00:00 authored by Slawomir Urban, Bernhard Beiring, Nuria Ortega, Daniel Paul, Frank Glorius

An efficient and highly asymmetric ruthenium-N-heterocyclic carbene-catalyzed hydrogenation of substituted thiophenes and benzothiophenes is described, providing a new strategy for the formation of valuable enantiomerically pure tetrahydrothiophenes and 2,3-dihydrobenzothiophenes.