Antioxidant and hyaluronidase inhibitory activities of diverse phenolics in <i>Phyllanthus emblica</i>

<p>Fifty-eight phenolic compounds isolated from <i>Phyllanthus emblica</i> were screened and compared for their <i>in vitro</i> and <i>in vivo</i> antioxidant properties, as well as hyaluronidase (HAase) inhibitory activities. Among them, 20 compounds showed to be promising antioxidants due to the stronger scavenging activity in both DPPH radical and <i>Danio rerio</i> reactive oxygen species assays, while nine compounds were potential HAase inhibitors with 100-fold stronger activities than that of the positive control, DSCG. The structure activity relationship was discussed.</p>