pntd.0005816.g004.tif (1.55 MB)
Analysis of genetic differentiation among 446 O. volvulus female worms from Ghana and Cameroon individually genotyped at 130 loci distributed throughout the genome.
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posted on 2017-07-26, 17:56 authored by Stephen R. Doyle, Catherine Bourguinat, Hugues C. Nana-Djeunga, Jonas A. Kengne-Ouafo, Sébastien D. S. Pion, Jean Bopda, Joseph Kamgno, Samuel Wanji, Hua Che, Annette C. Kuesel, Martin Walker, Maria-Gloria Basáñez, Daniel A. Boakye, Mike Y. Osei-Atweneboana, Michel Boussinesq, Roger K. Prichard, Warwick N. GrantMulti-dimensional scaling analysis was used to determine the relative genetic similarity between worms. Plots contain the same data, but have been presented to emphasise the degree of genetic differences between countries (A), sampling communities within each country (B), and their treatment exposure and phenotypic response to ivermectin if known (C). Ghanaian sampling sites: Asubende (ASU), Begbomdo (BEG), Jagbenbendo (JAG), Kyingakrom (KYG), New Longoro (NLG), and Wiae (WIA). Cameroonian sampling sites: Nkam valley (NKA07), Mbam valley sampled in 1994 (MBM94) before introduction of annual CDTI in 1994 and sampled in 2007 (MBM07).
