tbbb_a_1281003_sm2782.docx (17.62 kB)
Anaerobic biodegradation of spiramycin I and characterization of its new metabolites
journal contribution
posted on 2017-01-18, 09:33 authored by Jian Yao, Lei Shao, Daijie Chen, Pengyu Liu, Yubin ZhangActivated sludge was used to treat the wastewater containing spiramycin I. Three new metabolites were isolated and identified, which produced by oxidation of C6-aldehyde, hydrolysis of C5-mycaminose-mycarose and macrolactone ring-open reaction of spiramycin I in anaerobic digestion. And their antimicrobial activities were inactivated. Our results indicated that anaerobic biodegradation metabolites of spiramycin I could not induce bacterial resistance in environment.