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Alum-Catalyzed Domino Synthesis of 12-Substituted-8,9,10,12-tetrahydrobenzoxanthen-11-ones Under Solvent-Free Conditions

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Version 4 2014-10-21, 00:39
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journal contribution
posted on 2014-10-21, 00:39 authored by Rajan Kumar Sharma, Rajni Khajuria, Kamal K. Kapoor

Alum is found to catalyze efficiently the one-pot, three-component condensation of aldehydes, α/β-naphthol, and dimedone to afford various 12-substituted-8,9,10,12-tetrahydrobenzoxanthen-11-ones in excellent yields. The use of alum catalyst and the solvent-free conditions make this method simple, convenient, eco-friendly, and cost-effective.

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