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Alternative Approach to Synthesis of 3-(4-chloro butyl)-1H-indole-5-carbonitrile: A Key Intermediate of Vilazodone Hydrochloride, an Antidepressant Drug

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Version 4 2014-10-21, 00:39
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Version 2 2014-10-17, 21:59
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journal contribution
posted on 2014-10-21, 00:39 authored by N. Anitha, B. Sudhakar Reddy, N. M. Sekhar, K. Venugopal Reddy, E. R. R. Chandrasekhar

An alternative and efficient telescopic approach to the synthesis of 3-(4-chloro butyl)-1H-indole -5-carbonitrile (2), a key intermediate in the synthesis of vilazodone hydrochloride (1), is described.

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