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Ag+-Assisted Hydrosilylation: Complementary Behavior of Rh and Ir Catalysts (Reversal of Enantioselectivity)
journal contribution
posted on 2007-03-29, 00:00 authored by Anders Frölander, Christina MobergThe presence of a suitably situated hydroxy function in a PHOX ligand leads to an enhancement of the enantioselectivity in Rh-catalyzed
hydrosilylations of prochiral ketones in the presence of AgBF4 (95% ee for acetophenone as compared to 75% using i-Pr−phosphinooxazoline
(PHOX)). Exchanging Rh for Ir affords the product with the opposite absolute configuration (78% ee).