figshare
Browse
ol0702730_si_001.pdf (346.78 kB)

Ag+-Assisted Hydrosilylation:  Complementary Behavior of Rh and Ir Catalysts (Reversal of Enantioselectivity)

Download (346.78 kB)
journal contribution
posted on 2007-03-29, 00:00 authored by Anders Frölander, Christina Moberg
The presence of a suitably situated hydroxy function in a PHOX ligand leads to an enhancement of the enantioselectivity in Rh-catalyzed hydrosilylations of prochiral ketones in the presence of AgBF4 (95% ee for acetophenone as compared to 75% using i-Pr−phosphinooxazoline (PHOX)). Exchanging Rh for Ir affords the product with the opposite absolute configuration (78% ee).

History