Additional file 9: of Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration

Adaptive model analysis and ROC curve in HGB concentration (g·L−1) across 28 subjects (14 subjects × 2 trials) in the MDS. Red lines: individual limits as determined by the adaptive model for a specificity of 99%; blue line: actual test results. Subject A, D, F. G, J, K, M, P, R, S, U, X, Z and AA participated in the rHuEpo trial; subject B, C, E, H, I, L, N, O, Q, T, V, W, Y and BB participated in the placebo trial. X-axis: 13 time points and y-axis: HGB concentrations. (ZIP 88 kb)