Additional file 8: Figure S3. of High-density P300 enhancers control cell state transitions

A. A genome browser screenshot depicts a mouse SE which overlaps the Ccr7 gene and lncRNAs (or eRNAs) that are enriched in Th17 cells. Expression of these lncRNAs in Th17 cells depend on Stat3 or Batf, and these two transcription factors bind extensively throughout this locus and co-localize with P300. This locus also contains sequence homology to two human Th17 cell-specific SEs [4], mapped by synteny. Data are from [25]. (DOC 100 kb)