Additional file 7: of Echinococcus granulosus Antigen B binds to monocytes and macrophages modulating cell response to inflammation

Effects of EgAgB on IL-10 production by macrophages. THP-1 macrophages were stimulated with LPS (0.1 ng/ml) for 12 h in absence or presence of increasing concentrations of EgAgB. Secretion of IL-10 was determined by ELISA in cell culture supernatant and expressed as the fold-increase related to the basal secretion (normalised against the medium condition). Results correspond to mean values ± SEM of two independent experiments. Number signs (#) indicate significant differences with respect to the medium condition according to one-way ANOVA analysis followed by Tukey’s post-test (p < 0.05). (TIF 24 kb)