Additional file 7: of De novo assembly and characterization of breast cancer transcriptomes identifies large numbers of novel fusion-gene transcripts of potential functional significance

2017-08-29T05:00:00Z (GMT) by Vinay Mittal John McDonald
Cancer specific chimeric transcripts with fused 5′ or 3′ UTRs and having the ORF of the coding gene intact and displaying >2X change in expression relative to the intact gene’s expression in normal tissue. The first sheet in the excel file contains the key defining column entries. The second sheet contains data for chimeras with a fused 5′ UTR; the third sheet contains data for chimeras with a fused 3′ UTR. For 5′-UTR fusions, the expression fold change for the 3′ partner gene is calculated; for 3′ UTR fusions, the expression fold change for the 5′ partner gene is calculated. The upper portion in each data sheet summarizes the down-regulated genes and the lower portion summarizes the up-regulated genes. (XLSX 27 kb)