Additional file 7: Figure S7. of Identification and classification of small molecule kinases: insights into substrate recognition and specificity

The hyperpartitions that are examined in mcBPPS are given in the form of a tree in this figure. The newick format tree is converted into a hyperpartition, which determines the foreground and backgrounds used for determining the most distinguishing residues. For instance, APH2 family is used once as foreground with all ELKs as background, ignoring the EPK and APK groups. Similar analysis is also carried out for other ELK families. Note that as part of the analysis, EPK and PI3K patterns were also generated, but are not discussed. (PNG 42 kb)