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Additional file 6: Table S6. of Hyaluronic acid injection therapy for osteoarthritis of the knee: concordant efficacy and conflicting serious adverse events in two systematic reviews

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posted on 04.11.2016 by Claire O’Hanlon, Sydne Newberry, Marika Booth, Sean Grant, Aneesa Motala, Margaret Maglione, John FitzGerald, Paul Shekelle
Comparison of AE and SAE categorization in our review and the review by Rutjes and colleagues [8]. Both articles categorized AEs as serious or non-serious. Our review also categorized by locality (joint, non-joint local, or other). Both reviews omitted some SAEs that were qualitatively similar to SAEs counted by the other group. Our review excluded events only that did not describe the type of SAE that occurred. Rutjes et al. omitted some events that were similar to events they did count as SAEs. (DOCX 38 kb)

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