Additional file 6: Figure S5. of Pulmonary edema following central nervous system lesions induced by a non- mouse-adapted EV71 strain in neonatal BALB/c mice

ZZ1350 infection induced mucus production and alveolar space enlargement in mice lungs. Mucus production was determined by Masson’s Trichrome and PAS staining (A). Lm (B) was calculated based on 10 randomly selected fields in each section at 100× magnification with two crossed test lines. Data are expressed as mean ± SEM. *** P < 0.001, intracerebral (n = 15), intramuscular (n = 12), or intraperitoneal inoculation (n = 11) vs normal controls (n = 10). (TIFF 2944 kb)