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Additional file 6: Figure S1. of A systematic comparison of copy number alterations in four types of female cancer

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posted on 2016-11-22, 05:00 authored by Fatemeh Kaveh, Lars Baumbusch, Daniel Nebdal, Anne-Lise Børresen-Dale, Ole Lingjærde, Hege Edvardsen, Vessela Kristensen, Hiroko Solvang
Genomic Identification of Significant Targets (GISTIC) outputs for Circular Binary Segmentation (CBS) - or Piecewise Constant Fit (PCF) - segmented input data. The number of peaks attained by GISTIC on the y-axis is plotted against the two changing parameters α for CBS and γ for PCF on the x-axis. GISTIC peaks of amplification applying CBS-segmented data are illustrated in pink and PCF-segmented data in red, respectively. Deletion peaks are colored in green for CBS-segmented input data and in blue for PCF-segmented data. From top to bottom are shown GISTIC focal peaks for breast, ovarian, endometrial, and cervical cancers, to the left for PCF-segmented input data (A, C, E, and G) and to the right for CBS-segmented input data (B, D, F and H), respectively. For further analysis are the selected α and γ highlighted with a colored square. (PDF 362 kb)

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