13040_2015_74_MOESM5_ESM.xlsx (53.61 kB)
Additional file 5: Table S4. of Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)
dataset
posted on 2015-12-14, 05:00 authored by Rishika De, Shefali Verma, Fotios Drenos, Emily Holzinger, Michael Holmes, Molly Hall, David Crosslin, David Carrell, Hakon Hakonarson, Gail Jarvik, Eric Larson, Jennifer Pacheco, Laura Rasmussen-Torvik, Carrie Moore, Folkert Asselbergs, Jason Moore, Marylyn Ritchie, Brendan Keating, Diane Gilbert-DiamondResults from QMDR association analysis of main effect filtered SNP-SNP models replicated in eMERGE dataset. Shown here are models that reached a permutation P-valueâ<â0.05 in the replication dataset. SNPs have been mapped to their corresponding genes using dbSNP (build 139). SNP1 and SNP2 indicate the individual SNPs within a given SNP-SNP interaction model. P-values were calculated from a distribution built from 1000 permutations. (XLSX 53 kb)
