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Additional file 5: Table S2. of Transcriptome profiling of gene expression during immunisation trial against Fasciola hepatica: identification of genes and pathways involved in conferring immunoprotection in a murine model

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posted on 2017-01-23, 05:00 authored by Jose Rojas-Caraballo, Julio López-Abán, Darwin Moreno-Pérez, Belén Vicente, Pedro Fernández-Soto, Esther del Olmo, Manuel Patarroyo, Antonio Muro
The table lists the number of genes differentially expressed as a direct result of the immunisation trial. Differential expression has been calculated in each microarray by using the robust microarray analysis algorithm and the significance analysis of microarrays method. Up-regulated genes are shown in red whilst down-regulated are shown in green. Table S3. The Ingenuity Pathway Analysis tool was used for identifying the signalling pathways and their associated-genes differentially expressed by the immunisation trial. Up-regulation is shown in red whilst down-regulation is shown in green. Table S4. Biological functions and their associated genes differentially expressed by the immunisation trial were identified by using the Ingenuity Pathway Analysis tool. Up-regulation is shown in red whilst down-regulation is shown in green. Table S5. Immunisation of mice with a combination of peptides containing T-cell epitopes led to the differential expression of 37 genes (p <0.05; fold change +/− 2). Up-regulation is shown in red whilst down-regulation is shown in green. (XLSX 257 kb)

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