Additional file 5: Figure S5. of Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment

Tasquinimod inhibits MC38-C215 tumor growth in a T cell independent manner. Nude mice were inoculated s.c. with 0.5 × 106 MC38-C215 cells. Treatment with tasquinimod (30 mg/kg ad lib.) was initiated on the day of tumor inoculation and continued throughout the experiment (*p < 0.05; 2-way ANOVA). Tumor volume (left panel) measurements and tumor weight at the end of experiment (*p < 0.05; Mann Whitney) (right panel). (PDF 11 kb)