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Additional file 4: Figure S4. of Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae

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posted on 2017-01-28, 05:00 authored by Maria Zarcone, Annemarie van Schadewijk, Evert Duistermaat, Pieter Hiemstra, Ingeborg Kooter
TNFα-induced inflammatory, antimicrobial response and HSPA5/BiP induction. Cellular response of cultures from 5 non-COPD and 7 COPD donors treated for 3 h with 20 ng/ml of TNFα added to the basal medium. CXCL8 (4A), DEFB4A (4B), S100A7 (4C) and HSPA5/BiP (4D) mRNA expression is reported as fold from untreated controls after normalization on two reference genes, ATP5b and RPL13A. (PDF 524 kb)

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Lung foundation Netherlands

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    Respiratory Research

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    Keywords

    Airway epithelial cellsDiesel exhaustAir pollutionCOPDNon-typeable Haemophilus influenzaeIntegrated stress responseAntimicrobial responseAntimicrobial peptides

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