Additional file 4: Figure S3. of Continuous long-term cytotoxicity monitoring in 3D spheroids of beetle luciferase-expressing hepatocytes by nondestructive bioluminescence measurement

Daily changes of dose-response curves of ELuc bioluminescence from compound-treated 3D spheroids shown in Figs. 4–6. The concentration response curves for every 4 days were superimposed. (PPTX 154 kb)