13073_2016_345_MOESM4_ESM.pdf (546.39 kB)
Additional file 4: Figure S3. of Characterisation of the global transcriptional response to heat shock and the impact of individual genetic variation
journal contribution
posted on 2016-08-24, 05:00 authored by Peter Humburg, Narelle Maugeri, Wanseon Lee, Bert Mohr, Julian KnightNetwork analysis of HSF1 and relationship with observed differentially expressed genes in heat shock response. We constructed a network between HSF1 and observed differentially expressed genes following heat shock (1.2 FC, FDR <0.01) in LCLs using IPA, with lines denoting the shortest path between HSF1 and a particular molecule or the shortest path plus one molecule. Radial layout with the names of molecules showing multiple (nodal) relationships highlighted. Other individual molecules also shown. (PDF 546 kb)