13075_2016_914_MOESM4_ESM.eps (1.86 MB)
Additional file 4: Figure S1. of Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis
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posted on 2016-01-22, 05:00 authored by Michael Johnson, Andrew Grassetti, Jaclyn Taroni, Shawn Lyons, Devin Schweppe, Jessica Gordon, Robert Spiera, Robert Lafyatis, Paul Anderson, Scott Gerber, Michael WhitfieldNetwork analysis of systemic sclerosis (SSc) autoantigens. All 763 non-redundant peptide hits identified in two or more patients were analyzed using the Genome-scale Integrated Analysis of gene Networks in Tissues (GIANT) global network to identify functionally associated protein networks. Analysis of community function was performed using gProfiler. SSc-associated autoantibodies are highlighted in yellow. (EPS 1902 kb)