Additional file 3: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

Figure S3. (A) Immunoprecipitated mice whole brain lysates with anti-Znf179 antibody from wild-type and Znf179 knockout mice were separated by SDS-PAGE (4–20% polyacrylamide gel). Protein lands corresponding to immuno-positive bands were excised from gels (a, b, c and d bands), and analyzed with mass spectrometer. (B and C) Potential networks and involved subcellular pathways of identified proteins were further analyzed by IPA. (TIF 2176 kb)