40478_2016_399_MOESM3_ESM.doc (201.5 kB)
Additional file 3: of Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection
journal contribution
posted on 2016-12-12, 05:00 authored by Milos Ikonomovic, Chris Buckley, Kerstin Heurling, Paul Sherwin, Paul Jones, Michelle Zanette, Chester Mathis, William Klunk, Aruna Chakrabarty, James Ironside, Azzam Ismail, Colin Smith, Dietmar Thal, Thomas Beach, Gill Farrar, Adrian SmithROC Analysis - Dichotomised BIE (majority read) vs categorical neuropathology. Comparison of the 4 histopathological criteria of assigning abnormal amyloid against a dichotomised (Abnormal/Normal) majority blinded PET Image evaluation. The 4 criteria shown are CERAD [43], National Institutes of Ageing – Reagan Institute AD diagnosis [26], National Institutes of Ageing – Alzheimer’s Association AD diagnosis [25] and Amyloid phase (Phase 3 or greater) [58]. (DOC 201 kb)