Additional file 3: of Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

Intracellular localization of large Aβ42-555 inclusions in astrocytes. Intersections from a 3D z-stack of an astrocyte exposed to Aβ42-555 protofibrils demonstrate that Aβ42-555 deposits are located intracellularly (arrow heads). DAPI (blue), GFAP (green) and Aβ42-555 (red). Scale bars: 10 μm. (TIF 2239 kb)