Additional file 3: Figure S3. of Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

Exposure to UVB plus heat induced a significant decrease in acetylated p53 levels in NHEK and in skin models. Immunohistochemical staining of CPD (red), p53-a382 or SIRT1-p (green) and DAPI (blue) in untreated or UVB and/or heat treated NHEK. Cells co-expressing p53-a382/CPD are also indicated by green arrows. Scale bar (white line) =100 Οm. (JPG 304 kb)