40246_2015_48_MOESM2_ESM.pdf (381.94 kB)
Additional file 2 of Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype
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posted on 2015-10-13, 05:00 authored by Matahi Moarii, Fabien Reyal, Jean-Philippe VertStability of CIMP clusters with respect to the size of the CIMP signature. Robustness of cluster assignment for each sample (columns) as a function of the proportion of variant CGIs kept to define the CIMP signature, from 1 to 10 % (rows) and given the number of CIMP clusters considered (left panels: K = 2, right panels: K = 3, yellow = CIMP-positive, blue = CIMP-negative, black = CIMP-low) for bladder (panel A/B), breast (panel C/D), colon (panel E/F), lung (panel G/H), stomach (panel I/J). Panel K. Table summarizing the stability of the cluster assignments for each tissue and different number of CIMP clusters considered. (PDF 381 kb)
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