Additional file 2: Table S1. of Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

Relative risk and TtD of case sub-groups with different B-cell fraction. Table S2. Numbers of differential signals observed in different subject groups. Table S3. Top 100 DM CpGs. Table S4. Genes and CGI’s with at least three DM CpG sites and 20% enrichment. Table S5. CLL risk-related DE probes (FDR < 0.05). Table S6. CLL risk-associated DM and DE signals in cases with <10% B-cells compared to controls with <10% B-cells; Table S7. Top 100 DM and DE signals significant at FDR < 0.05 in the long and short TtD subgroups. Table S8. Methylation multiplicity, in the long and short TtD subgroups. Table S9. Ontology terms and pathways derived from the DM genes. Table S10. Ontology terms and pathways derived from the DE genes. Table S11. Ontology terms and pathways derived from the DM genes significant in different TtD subgroups. Table S12. Ontology terms and pathways derived from the DE genes significant in the short TtD subgroup. Table S13. CLL risk-related DM & DE hub genes. Table S14. DM and DE hub genes significant in different TtD subgroups. (XLSX 115 kb)