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Additional file 2: Figure S2. of Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

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posted on 2016-03-31, 05:00 authored by Mohadeseh Hasanpourghadi, Chandrabose Karthikeyan, Ashok Pandurangan, Chung Looi, Piyush Trivedi, Kinue Kobayashi, Kozo Tanaka, Won Wong, Mohd Mustafa
Molecular docking of MBIC with tubulin complex. Hydrogen bonds between amino acids of tubulin complex and MBIC. Molecular structure was visualized by UCSF Chimera 1.8.1 program. Figure (A) is showing ribbon representation of tubulin-MBIC complex. Figure (B) is showing hydrogen bonds (green line) of MBIC with surrounding amino acids residues which are included polar lysine 352 and hydrophobic valine 181 amino acids. (PDF 3179 kb)

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Ministry of Higher Education, Malaysia (MOHE)

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