Additional file 2: Figure S2. of Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway

RSV in combination with etoposide (ETO) has synergistic effect on cell proliferation and DDR in NKTCL cells. A. SNT-8 and SNK-10 cells were incubated with RSV (25 μM), etoposide (ETO, 1 μM), or RSV in combination with etoposide (RSV + ETO). After 24 and 48 h, cell viability was determined using CCK-8 assay. Each value represents the mean ± SD of 3 independent experiments. B. SNT-8 and SNK-10 Cells were incubated with RSV (25 μM), etoposide (ETO, 1 μM), or RSV in combination with etoposide (RSV + ETO) for 6 h. The protein levels of pATM (S1981), ATM, γH2A.X (S139), pChk2 (T68), pp53 (S15), p53 were monitored. *p < 0.05 RSV + ETO vs RSV, # p < 0.05 RSV + ETO vs ETO. (TIFF 3788 kb)