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Additional file 2: Figure S2. of Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway

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posted on 2017-09-26, 05:00 authored by Xianxian Sui, Canjing Zhang, Jianan Zhou, Shengxuan Cao, Chen Xu, Feng Tang, Xiuling Zhi, Bobin Chen, Songmei Wang, Lianhua Yin
RSV in combination with etoposide (ETO) has synergistic effect on cell proliferation and DDR in NKTCL cells. A. SNT-8 and SNK-10 cells were incubated with RSV (25 μM), etoposide (ETO, 1 μM), or RSV in combination with etoposide (RSV + ETO). After 24 and 48 h, cell viability was determined using CCK-8 assay. Each value represents the mean ± SD of 3 independent experiments. B. SNT-8 and SNK-10 Cells were incubated with RSV (25 μM), etoposide (ETO, 1 μM), or RSV in combination with etoposide (RSV + ETO) for 6 h. The protein levels of pATM (S1981), ATM, γH2A.X (S139), pChk2 (T68), pp53 (S15), p53 were monitored. *p < 0.05 RSV + ETO vs RSV, # p < 0.05 RSV + ETO vs ETO. (TIFF 3788 kb)

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National Natural Science Foundation of China

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