Additional file 2: Figure S2. of Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death

eGFP-NEFH WT form filamentous network in vitro and in ovo. A. monomeric eGFP tag NEFH WT expression can form visible filamentous network in SH-EP under lower expression condition when transfected at low concentration (optimal recommended concentration diluted four time). eGFP-NEFH WT form filamentous network in spinal motoneuron in vitro (B) and in vivo (C). Scale bar 10 μm. (TIFF 156 kb)