Additional file 2: Figure S2. of Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes

Whole mount immunofluorescence for the pan endothelial cell marker CD31 in endometriotic lesions, uterus and ovary. (A) Endometriotic lesions have a robust, disorganized vascular network. (B) The mouse ovary is highly vascularized, but the blood vessels have a more uniform appearance, and an even distribution throughout the organ compared to an endometriotic lesion. (C) Anti-mesometrial view of the mouse uterus. The myometrium contains few blood vessels compared to the endometrium, which is also highly vascularized. Images are magnified 100× and scale bars represent 100 μm. AMM: Anti-mesometrial myometrium; AME: Anti-mesometrial endometrium. (TIF 510 kb)