Additional file 2: Figure S1. of Sex-specific phenotypes of hyperthyroidism and hypothyroidism in aged mice

Food intake behaviour during experimental procedure influenced by sex, age and TH condition. Food intake was related to BW weekly in (A-C) adult and (D-F) old male and female mice. Sex dependency was noted for euthyroid groups (for adult: F(8,108) = 24.92 for time, F(1,108) = 430.6 for sex effect, F(8,108) = 9.204 for interaction, p < 0.001; for old: F(8,134) = 15.75 for time, F(1,134) = 51.5 for sex effect, F(8,134) = 1.783 for interaction, p = 0.0857), which disappeared by TH excess and deprivation. Data are presented as mean ± SD, n = 7-11 animals/sex/treatment, 2-way ANOVA followed by Bonferroni post hoc analysis, *p < 0.05, **p < 0.01, ***p < 0.001. (TIFF 743 kb)