Additional file 1: Figure S1. of Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy

Behrouzi, Roya; Liu, Xiawei; Wu, Dongyue; Robinson, Andrew; Tanaguchi-Watanabe, Sayuri; Rollinson, Sara; Shi, Jing; Tian, Jinzhou; Hamdalla, Hisham; Ealing, John; Richardson, Anna; Jones, Matthew; Pickering-Brown, Stuart; Davidson, Yvonne; Strong, Michael; Hasegawa, Masato; Snowden, Julie; Mann, David

doi:10.6084/m9.figshare.c.3639104_D2.v1

40478_2016_301_MOESM1_ESM.docx (6.35 MB)

Additional file 1: Figure S1. of Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy

journal contribution

posted on 2016-03-31, 05:00 authored by Roya Behrouzi, Xiawei Liu, Dongyue Wu, Andrew Robinson, Sayuri Tanaguchi-Watanabe, Sara Rollinson, Jing Shi, Jinzhou Tian, Hisham Hamdalla, John Ealing, Anna Richardson, Matthew Jones, Stuart Pickering-Brown, Yvonne Davidson, Michael Strong, Masato Hasegawa, Julie Snowden, David Mann

Îą-synuclein (a-c) pathology in cingulate gyrus (a), CA2 region of hippocampus (b) and substantia nigra (c) and TDP-43 pathology in anterior horn cells of the spinal cord (d-f), with fine, particulate accumulations of TDP-43 (d,e) or skein-like structures (e,f) being present in affected cells in which the nucleus has been âclearedâ of its normal immunoreactivity. Immunoperoxidase, x400 microscope magnification. (DOCX 6504Â kb)