Additional file 1: Figure S1. of Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias

CRMP2 is concentrated in cytosol-enriched fractions of postmortem human neocortex. Representative CRMP2 immunoblots of total and cytosol-enriched (“Cytosolic”) fractions of postmortem human neocortex (5 μg protein loaded per lane). β-actin was used as a control to show concentration of soluble cytoskeletal proteins, including CRMP2, in the cytosol-enriched fractions using the fractionation procedure described in Methods. (PDF 116 kb)