Additional file 1: Figure S1. of Impact of post-alignment processing in variant discovery from whole exome data

Change of INDEL calling precision rate following local realignment. Figure S2: Local realignment and BQSR for SAMtools/BCFtools consensus-caller and multiallelic-caller. Figure S3: BQSR changed variant calling sensitivity in NA12878. Figure S4: Change of known and novel SNPs in NA12878 after BQSR. Figure S5: Change of known and novel INDELs in NA12878 by BQSR. Figure S6: Local realignment and BQSR with hg19 versus hg38. (PDF 769 kb)