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Additional file 1: Figure S1. of IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans

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posted on 2016-10-07, 05:00 authored by Rafael Ferraz, Henrique Camara, Evandro De-Souza, Silas Pinto, Ana Pinca, Richard Silva, Vitor Sato, Beatriz Castilho, Marcelo Mori
The IMPACT protein of Caenorhabditis elegans. (a) Alignment between the amino acid sequences of mouse protein IMPACT (sbjct) and Y52B11A.2 of C. elegans (query). Result show 33 % identity and 51 % similarity between both proteins (E value of 7e–55). (b) Predicted domains of C. elegans Y52B11A.2. (PDF 270 kb)

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Fundação de Amparo à Pesquisa do Estado de São Paulo

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    BMC Biology

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    Keywords

    IMPACTGCN2Dietary restrictionIntegrated stress responseAging

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