Additional file 1: Figure S1. of A T-type channel-calmodulin complex triggers αCaMKII activation

Asmara, Hadhimulya; Micu, Ileana; Rizwan, Arsalan; Sahu, Giriraj; Simms, Brett; Zhang, Fang-Xiong; Engbers, Jordan; Stys, Peter; Zamponi, Gerald; Turner, Ray

doi:10.6084/m9.figshare.c.3851797_D1.v1

13041_2017_317_MOESM1_ESM.pdf (828.08 kB)

Additional file 1: Figure S1. of A T-type channel-calmodulin complex triggers αCaMKII activation

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posted on 2017-08-11, 05:00 authored by Hadhimulya Asmara, Ileana Micu, Arsalan Rizwan, Giriraj Sahu, Brett Simms, Fang-Xiong Zhang, Jordan Engbers, Peter Stys, Gerald Zamponi, Ray Turner

Cav3.1 channels exhibit a calcium-dependent association with CaM. a, b. Tests for coimmunoprecipitation between Cav3.1 channels and CaM from rat brain lysate (a) or homogenates of tsA-201 cells coexpresssing Cav3.1 and CaM (b) in the presence of the indicated buffered levels of calcium. Cav3.1 coimmunoprecipitates with CaM in 0 and 100 nM calcium but not at 50 μM or 1 mM calcium. All results were derived from at least 3 separate experiments. (PDF 828 kb)

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Calmodulin Cav3.1 T-type channel αCaMKII Hippocampus Purkinje cell Cerebellum

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Additional file 1: Figure S1. of A T-type channel-calmodulin complex triggers αCaMKII activation

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