Additional file 1: Figure S1A. of 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

Gangadhara, Sharath; Smith, Chris; Barrett-Lee, Peter; Hiscox, Stephen

doi:10.6084/m9.figshare.c.3631220_D3.v1

12885_2016_2377_MOESM1_ESM.doc (41.5 kB)

Additional file 1: Figure S1A. of 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

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posted on 2016-06-01, 05:00 authored by Sharath Gangadhara, Chris Smith, Peter Barrett-Lee, Stephen Hiscox

3D ‘On-Top’ Cell culture method. A modified version of the ‘3D on-top’ assay reported by Lee et al. [17] was used for analysis of cellular growth in 3D culture and optimised for the cell lines under test here. (DOC 41 kb)

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3D culture Her2+ breast cancer MAPK AKT Therapeutic response

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Additional file 1: Figure S1A. of 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response

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