Additional file 15: of Unexpected patterns of segregation distortion at a selfish supergene in the fire ant Solenopsis invicta

Figure S9. Hypothetical scenario for additive genetic mechanism of Sb supergene drive reversal in polygyne Solenopsis invicta. The presence of seven suppressor loci segregating wild-type alleles (ineffective in suppressing Sb drive) along with suppressor alleles is depicted as an example of such a multilocus system, with several different multilocus haplotypes arising from recombination and segregation in the population illustrated. The inset depicts the distribution of multilocus haplotypes with varying proportions of suppressor alleles expected in an equilibrium population of 5000 haplotypes with the seven suppressor loci in gametic equilibrium, equal allele frequencies, and no selection. Haplotypes with no or very few suppressor alleles allow Sb drive to prevail, those with high or maximal numbers of suppressor alleles overwhelm Sb drive to cause drive reversal, and those with intermediate proportions of suppressor alleles (the most common circumstance―inset) neutralize Sb drive to favor Mendelian segregation ratios. The suppressor loci are shown in the region of SB chromosome 16 homologous to the supergene (see Additional file 13: Text S3 for rationale). Centromere is not shown to scale (see Additional file 5: Figure S2). (TIF 781 kb)