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Additional file 13: Figure S8. of Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation

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posted on 2015-08-26, 05:00 authored by M. Brahimi-Horn, Sandy Giuliano, Estelle Saland, Sandra Lacas-Gervais, Tatiana Sheiko, Joffrey Pelletier, Isabelle Bourget, Frédéric Bost, Chloé Féral, Etienne Boulter, Michel Tauc, Mircea Ivan, Barbara Garmy-Susini, Alexandra Popa, Bernard Mari, Jean-Emmanuel Sarry, William Craigen, Jacques Pouysségur, Nathalie Mazure
Knockout of Vdac1 significantly disrupted apoptosis. Immunofluorescence to cytochrome C and DAPI in Wt and Vdac1 −/− MEF in Nx.

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