Additional file 12: Figure S5. of Identification of global regulators of T-helper cell lineage specification

Randomization test of epigenetic marks around lineage-specific lncRNAs. a Randomization test reveals that the number of lineage-specific enhancers around lineage-specific lncRNAs is more than anywhere else in the genome. b Randomization test reveals that the number of lineage-specific promoters around the lineage-specific lncRNAs is more than anywhere else in the genome. The distribution of enhancers or promoters in the vicinity of genes in the genome was determined by randomly picking the same number of genes as in the lineage-specific set. The red dashed line indicates the number of lineage-specific enhancers or promoters found in the vicinity of lineage-specific lncRNAs. (PDF 114 kb)