Additional file 11: of A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

cFb-IC-induced TNF-Îą production was inhibited by TLR4 blockade with NI-0101. Fc-dependent mechanism of action rendered NI-0101 a more effective antibody in inhibiting cFb-IC-stimulated TNF-Îą production from macrophages. (DOCX 150 kb)