Acremostrictin, a Highly Oxygenated Metabolite from the Marine Fungus Acremonium strictum
2011-12-27T00:00:00Z (GMT) by
The novel natural product acremostrictin (1) was isolated from the culture broth of Acremonium strictum, a marine fungus collected from a Choristida sponge off the coast of Korea. Structurally, acremostrictin is a tricyclic lactone of an unprecedented skeletal class based on combined spectroscopic and X-ray crystallographic analyses. The new compound exhibited weak antibacterial and moderate antioxidant activities.