tgcl_a_1526332_sm1533.docx (898.76 kB)
A solvent-free synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one in a ball mill
journal contribution
posted on 2018-10-08, 13:25 authored by Xiong Zhang, Biao Wang, Binbin Zhang, Yifeng WangAn easy, solvent-free method for the synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one has been achieved by grinding 4-chlorophenyl hydrazine and methyl acrylate in the presence of base in a ball mill. A systematic investigation of the reaction has been made in order to study the various factors affecting the reaction.