ganp_a_1367771_sm9832.doc (1.04 MB)
A novel chloro-substituted pentenamide from the fruiting bodies of Amanita virgineoides
journal contribution
posted on 2017-09-04, 11:11 authored by Liang-Yan Liu, Ji-Kai Liu, Wen-Han Su, Tao PengOne unusual chloro-substituted pentenamide, (3R)-4-chloro-3-hydroxy-4-pentenamide (1), together with 11 known compounds (2–12) were isolated from the fruiting bodies of Amanita virgineoides. The structure of 1 including the absolute configuration was characterized by extensive spectroscopic analyses and quantum calculation. Compound 1 displayed no obvious activity against herpes simplex virus (HSV), human enterovirus 71 (EV71) or coxsackievirus B3 (CVB3).