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A new tremulane sesquiterpenoid from the fungus Irpex lacteus

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journal contribution
posted on 2018-03-09, 11:47 authored by Jian-Hai Ding, Zheng-Hui Li, Tao Feng, Ji-Kai Liu

A new tremulane sesquiterpenoid, named irlactam A (1), was isolated from cultures of the fungus Irpex lacteus. The new structure was elucidated by spectroscopic data analysis. The compound was tested for its cytotoxicities on HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells and for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases (11β-HSD).

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