A new sesquiterpene from the South China Sea gorgonian coral <i>Subergorgia suberosa</i>

2016-05-31T12:59:45Z (GMT) by Mu-Wu Xu Yuan-Tao Hao
<p>A new sesquiterpene, namely suberosoid (<b>1</b>), was isolated from the South China Sea gorgonian coral <i>Subergorgia suberosa</i>. The chemical structure of <b>1</b> was established as an unusual sesquiterpene containing 4-methylenecyclohex-2-enone system, by extensive analyses of NMR spectroscopy and high-resolution mass spectrometry. Suberosoid (<b>1</b>) exhibited cytotoxic effect against HeLa cell lines with IC<sub>50</sub> value being 10.6 μM.</p>